Package: CaDrA
Type: Package
Title: Candidate Driver Analysis
Version: 1.2.0
Date: 2022-11-20
Authors@R: 
    c(person(given="Reina", family="Chau", role=c("aut","cre"), 
             email="rchau88@bu.edu", comment=c(ORCID="0000-0003-3012-1404")), 
      person(given="Katia", family="Bulekova", role=c("aut"), 
             email="ktrn@bu.edu", comment=c(ORCID="0000-0003-1560-2146")),
      person(given="Vinay", family="Kartha", role=c("aut"), 
             email="vkartha@bu.edu"), 
      person(given="Stefano", family="Monti", role=c("aut"), 
             email="smonti@bu.edu", comment=c(ORCID="0000-0002-9376-0660"))
     )
Description: Performs both stepwise and backward heuristic search for 
    candidate (epi)genetic drivers based on a binary multi-omics dataset. 
    CaDrA's main objective is to identify features which, together, are 
    significantly skewed or enriched pertaining to a given vector of 
    continuous scores (e.g. sample-specific scores representing a phenotypic 
    readout of interest, such as protein expression, pathway activity, etc.), 
    based on the union occurence (i.e. logical OR) of the events.
Depends: R (>= 4.3.0)
LazyData: false
License: GPL-3 + file LICENSE
URL: https://github.com/montilab/CaDrA/
Packaged: 2024-05-01 21:33:58 UTC; biocbuild
Encoding: UTF-8
RoxygenNote: 7.3.1
Imports: doParallel, ggplot2, gplots, graphics, grid, gtable, MASS,
        methods, misc3d, plyr, ppcor, R.cache, reshape2, stats,
        SummarizedExperiment
Suggests: BiocManager, devtools, knitr, pheatmap, rmarkdown, testthat
        (>= 3.1.6)
Config/testthat/edition: 3
biocViews: Microarray, RNASeq, GeneExpression, Software,
        FeatureExtraction
VignetteBuilder: knitr
BugReports: https://github.com/montilab/CaDrA/issues
git_url: https://git.bioconductor.org/packages/CaDrA
git_branch: RELEASE_3_19
git_last_commit: 829da92
git_last_commit_date: 2024-04-30
Repository: Bioconductor 3.19
Date/Publication: 2024-05-01
NeedsCompilation: yes
Author: Reina Chau [aut, cre] (<https://orcid.org/0000-0003-3012-1404>),
  Katia Bulekova [aut] (<https://orcid.org/0000-0003-1560-2146>),
  Vinay Kartha [aut],
  Stefano Monti [aut] (<https://orcid.org/0000-0002-9376-0660>)
Maintainer: Reina Chau <rchau88@bu.edu>
Built: R 4.4.0; x86_64-w64-mingw32; 2024-05-02 12:32:12 UTC; windows
Archs: x64
