Package: methylclock
Type: Package
Title: Methylclock - DNA methylation-based clocks
Version: 1.14.0
Authors@R: c( person("Dolors", "Pelegri-Siso", , "dolors.pelegri@isglobal.org", 
                      role = c("aut", "cre"), 
                      comment = c(ORCID = "0000-0002-5993-3003")),
              person("Juan R.", "Gonzalez", ,"juanr.gonzalez@isglobal.org", 
                     role = c("aut"), 
                     comment = c(ORCID = "0000-0003-3267-2146"))
              )
Description: This package allows to estimate chronological and gestational DNA methylation
       (DNAm) age as well as biological age using different methylation clocks.
       Chronological DNAm age (in years) : Horvath's clock, Hannum's clock, BNN, 
       Horvath's skin+blood clock, PedBE clock and Wu's clock.
       Gestational DNAm age : Knight's clock, Bohlin's clock, Mayne's clock and Lee's clocks.
       Biological DNAm clocks : Levine's clock and Telomere Length's clock.
biocViews: DNAMethylation, BiologicalQuestion, Preprocessing,
        StatisticalMethod, Normalization
License: MIT + file LICENSE
Depends: R (>= 4.1.0), methylclockData, devtools, quadprog
Imports: Rcpp (>= 1.0.6), ExperimentHub, dplyr, impute,
        PerformanceAnalytics, Biobase, ggpmisc, tidyverse, ggplot2,
        ggpubr, minfi, tibble, RPMM, stats, graphics, tidyr, gridExtra,
        preprocessCore, dynamicTreeCut, planet
Suggests: BiocStyle, knitr, GEOquery, rmarkdown
LinkingTo: Rcpp
Encoding: UTF-8
RoxygenNote: 7.1.2
URL: https://github.com/isglobal-brge/methylclock
BugReports: https://github.com/isglobal-brge/methylclock/issues
VignetteBuilder: knitr
git_url: https://git.bioconductor.org/packages/methylclock
git_branch: RELEASE_3_21
git_last_commit: d6eec3a
git_last_commit_date: 2025-04-15
Repository: Bioconductor 3.21
Date/Publication: 2025-04-15
NeedsCompilation: yes
Packaged: 2025-04-16 02:02:28 UTC; biocbuild
Author: Dolors Pelegri-Siso [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-5993-3003>),
  Juan R. Gonzalez [aut] (ORCID: <https://orcid.org/0000-0003-3267-2146>)
Maintainer: Dolors Pelegri-Siso <dolors.pelegri@isglobal.org>
Built: R 4.5.0; x86_64-w64-mingw32; 2025-04-16 14:51:53 UTC; windows
Archs: x64
