Package: vmrseq
Type: Package
Title: Probabilistic Modeling of Single-cell Methylation Heterogeneity
Version: 1.0.1
Authors@R: person("Ning", "Shen", email = "ning.shen.wk@gmail.com",role = c("aut", "cre"))
Description: High-throughput single-cell measurements of DNA methylation allows studying inter-cellular epigenetic heterogeneity, but this task faces the challenges of sparsity and noise. We present vmrseq, a statistical method that overcomes these challenges and identifies variably methylated regions accurately and robustly.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.2.3
biocViews: Software, ImmunoOncology, DNAMethylation, Epigenetics,
        SingleCell, Sequencing, WholeGenome
Depends: R (>= 4.5.0)
Imports: bumphunter, dplyr, BiocParallel, DelayedArray, GenomicRanges,
        ggplot2, methods, tidyr, locfit, gamlss.dist, recommenderlab,
        HDF5Array, data.table, SummarizedExperiment, IRanges, S4Vectors
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
Config/testthat/edition: 3
VignetteBuilder: knitr
URL: https://github.com/nshen7/vmrseq
BugReports: https://github.com/nshen7/vmrseq/issues
git_url: https://git.bioconductor.org/packages/vmrseq
git_branch: RELEASE_3_21
git_last_commit: 2e21cc1
git_last_commit_date: 2025-04-30
Repository: Bioconductor 3.21
Date/Publication: 2025-05-08
NeedsCompilation: no
Packaged: 2025-05-09 03:12:23 UTC; biocbuild
Author: Ning Shen [aut, cre]
Maintainer: Ning Shen <ning.shen.wk@gmail.com>
Built: R 4.5.0; ; 2025-05-09 14:19:28 UTC; windows
