Package: betaHMM
Type: Package
Title: A Hidden Markov Model Approach for Identifying Differentially
        Methylated Sites and Regions for Beta-Valued DNA Methylation
        Data
Version: 1.6.0
Authors@R: c(person("Koyel","Majumdar",email="koyelmajumdar.phdresearch@gmail.com",
        role=c("cre","aut"),comment = c(ORCID = "0000-0001-6469-488X")),
        person("Romina","Silva",
        role="aut"),
        person("Antoinette Sabrina","Perry",
        role="aut"),
        person("Ronald William","Watson",
        role="aut"),
        person("Isobel Claire","Gorley",email="claire.gormley@ucd.ie",
        role="aut", comment=c(ORCID="0000-0001-7713-681X")),
        person("Thomas Brendan","Murphy",email="brendan.murphy@ucd.ie", 
        role="aut",comment=c(ORCID="0000-0002-5668-7046")),
        person("Florence","Jaffrezic",email="florence.jaffrezic@inrae.fr",
        role="aut"),
        person("Andrea","Rau",email="andrea.rau@inrae.fr",role="aut",
        comment = c(ORCID = "0000-0001-6469-488X")))
Description: A novel approach utilizing a homogeneous hidden Markov
        model. And effectively model untransformed beta values. To
        identify DMCs while considering the spatial. Correlation of the
        adjacent CpG sites.
License: GPL-3
Encoding: UTF-8
Imports: stats, ggplot2, scales, methods, pROC, foreach, doParallel,
        parallel, cowplot, dplyr, tidyr, tidyselect, stringr, utils
Depends: R (>= 4.3.0), SummarizedExperiment, S4Vectors, GenomicRanges
RoxygenNote: 7.2.3
biocViews: DNAMethylation, DifferentialMethylation, ImmunoOncology,
        BiomedicalInformatics, MethylationArray, Software,
        MultipleComparison, Sequencing, Spatial, Coverage, GeneTarget,
        HiddenMarkovModel, Microarray
Suggests: rmarkdown, knitr, testthat (>= 3.0.0), BiocStyle
VignetteBuilder: knitr
Config/testthat/edition: 3
Config/pak/sysreqs: libicu-dev zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 15:27:06 UTC
RemoteUrl: https://github.com/bioc/betaHMM
RemoteRef: RELEASE_3_22
RemoteSha: 5800324d28b029bd091cd760ea7e1eab5cc861b3
NeedsCompilation: no
Packaged: 2026-03-04 08:41:00 UTC; root
Author: Koyel Majumdar [cre, aut] (ORCID:
    <https://orcid.org/0000-0001-6469-488X>),
  Romina Silva [aut],
  Antoinette Sabrina Perry [aut],
  Ronald William Watson [aut],
  Isobel Claire Gorley [aut] (ORCID:
    <https://orcid.org/0000-0001-7713-681X>),
  Thomas Brendan Murphy [aut] (ORCID:
    <https://orcid.org/0000-0002-5668-7046>),
  Florence Jaffrezic [aut],
  Andrea Rau [aut] (ORCID: <https://orcid.org/0000-0001-6469-488X>)
Maintainer: Koyel Majumdar <koyelmajumdar.phdresearch@gmail.com>
Built: R 4.5.2; ; 2026-03-04 08:42:34 UTC; windows
