Package: scDDboost
Type: Package
Title: A compositional model to assess expression changes from
        single-cell rna-seq data
Version: 1.12.0
Date: 2018-10-31
Authors@R: c(person("Xiuyu","Ma",email="watsonforfun@gmail.com",role = c("cre", "aut")),person(given = "Michael A.",family = "Newton", email="newton@stat.wisc.edu",role = "ctb"))
Description: scDDboost is an R package to analyze changes in the
        distribution of single-cell expression data between two
        experimental conditions. Compared to other methods that assess
        differential expression, scDDboost benefits uniquely from
        information conveyed by the clustering of cells into cellular
        subtypes. Through a novel empirical Bayesian formulation it
        calculates gene-specific posterior probabilities that the
        marginal expression distribution is the same (or different)
        between the two conditions. The implementation in scDDboost
        treats gene-level expression data within each condition as a
        mixture of negative binomial distributions.
License: GPL (>= 2)
Imports: Rcpp (>= 0.12.11), RcppEigen (>= 0.3.2.9.0),EBSeq,
        BiocParallel, mclust, SingleCellExperiment, cluster, Oscope,
        SummarizedExperiment, stats, methods
biocViews: SingleCell, Software, Clustering, Sequencing,
        GeneExpression, DifferentialExpression, Bayesian
Depends: R (>= 4.2), ggplot2
LinkingTo: Rcpp, RcppEigen, BH
Suggests: knitr, rmarkdown, BiocStyle, testthat
SystemRequirements: c++14
Roxygen: list(wrap=FALSE)
RoxygenNote: 7.1.2
VignetteBuilder: knitr
BugReports: https://github.com/wiscstatman/scDDboost/issues
URL: https://github.com/wiscstatman/scDDboost
Config/pak/sysreqs: make zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 15:17:12 UTC
RemoteUrl: https://github.com/bioc/scDDboost
RemoteRef: RELEASE_3_22
RemoteSha: 2aff65c5f758e7a29c4081df5198b7a121d3c399
NeedsCompilation: yes
Packaged: 2026-02-24 08:23:20 UTC; root
Author: Xiuyu Ma [cre, aut],
  Michael A. Newton [ctb]
Maintainer: Xiuyu Ma <watsonforfun@gmail.com>
Built: R 4.5.2; x86_64-w64-mingw32; 2026-02-24 08:25:33 UTC; windows
Archs: x64
