Package: GOTHiC
Title: Binomial test for Hi-C data analysis
Description: This is a Hi-C analysis package using a cumulative
        binomial test to detect interactions between distal genomic
        loci that have significantly more reads than expected by chance
        in Hi-C experiments. It takes mapped paired NGS reads as input
        and gives back the list of significant interactions for a given
        bin size in the genome.
Version: 1.46.0
Date: 2025-07-22
Author: Borbala Mifsud and Robert Sugar
Maintainer: Borbala Mifsud <b.mifsud@qmul.ac.uk>
Depends: R (>= 3.5.0), methods, GenomicRanges, Biostrings, BSgenome,
        data.table
Imports: BiocGenerics, S4Vectors (>= 0.9.38), IRanges, Rsamtools,
        ShortRead, rtracklayer, ggplot2, BiocManager, grDevices, utils,
        stats, Seqinfo
Suggests: HiCDataLymphoblast
Enhances: parallel
License: GPL-3
biocViews: ImmunoOncology, Sequencing, Preprocessing, Epigenetics, HiC
Config/pak/sysreqs: make libbz2-dev libjpeg-dev liblzma-dev libpng-dev
        libxml2-dev libssl-dev xz-utils zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 14:52:56 UTC
RemoteUrl: https://github.com/bioc/GOTHiC
RemoteRef: RELEASE_3_22
RemoteSha: 9a54459859dfab7f2ef1ef38b7596e394a3838f1
NeedsCompilation: no
Packaged: 2026-02-23 09:47:42 UTC; root
Built: R 4.5.2; ; 2026-02-23 09:49:57 UTC; windows
