Package: MEB
Type: Package
Title: A normalization-invariant minimum enclosing ball method to
        detect differentially expressed genes for RNA-seq and scRNA-seq
        data
Version: 1.24.0
Author: Yan Zhou, Jiadi Zhu
Maintainer: Jiadi Zhu <2160090406@email.szu.edu.cn>, Yan Zhou
 <zhouy1016@szu.edu.cn>
Description: This package provides a method to identify differential
        expression genes in the same or different species. Given that
        non-DE genes have some similarities in features, a scaling-free
        minimum enclosing ball (SFMEB) model is built to cover those
        non-DE genes in feature space, then those DE genes, which are
        enormously different from non-DE genes, being regarded as
        outliers and rejected outside the ball. The method on this
        package is described in the article 'A minimum enclosing ball
        method to detect differential expression genes for RNA-seq
        data'. The SFMEB method is extended to the scMEB method that
        considering two or more potential types of cells or unknown
        labels scRNA-seq dataset DEGs identification.
License: GPL-2
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.6.0)
Suggests: knitr,rmarkdown,BiocStyle
VignetteBuilder: knitr
RoxygenNote: 7.2.3
Imports: e1071, edgeR, scater, stats, wrswoR, SummarizedExperiment,
        SingleCellExperiment
biocViews: DifferentialExpression, GeneExpression, Normalization,
        Classification, Sequencing
Config/pak/sysreqs: libcairo2-dev libfontconfig1-dev libfreetype6-dev
        libfribidi-dev libharfbuzz-dev libicu-dev libjpeg-dev
        libpng-dev libtiff-dev libwebp-dev zlib1g-dev
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2025-10-29 14:54:34 UTC
RemoteUrl: https://github.com/bioc/MEB
RemoteRef: RELEASE_3_22
RemoteSha: 75bb07cc6ee7381e8298cb9ce9cbd0cf9f95c42f
NeedsCompilation: no
Packaged: 2026-02-23 09:05:27 UTC; root
Built: R 4.5.2; ; 2026-02-23 09:07:21 UTC; windows
